I had the typical bulls-eye rash from a tick and didn’t realize that it was Lyme until like a year later. At that time, I told my doc and he gave me 30 days of Doxycycline, however the side effects were terrible. Fast forward about 5 years, I have a tooth infection that went to my ear and was given Amoxicillin, Ery-Tabs, Keflex and had bad reactions to all of them (chest pain, rapid heartbeat, palpitations, high blood pressure). I asked this question differently before without mentioning the Lyme and someone thought it could be Mitral Valve Prolapse. However, is it common for people with Lyme Disease to be very, very sensitive to medications. I have also been prescribed meds for anxiety and depression and had a bad reaction to like at least 7 or 8 of them. Could the Lyme be fighting the antibiotics? Does that mean I should keep taking them, even though the side effects are that bad? I just got a new script.